Single-cell Opto-electric Recording

Single-cell recordings require an optical fiber core diameter at the fiber end comparable with the size of the cell under observation. The electrode tip has to be of the similar size and in close proximity to the fiber core. One way to achieve those specifications is by making a dual core optical fiber having the light guiding core and the capil...

Single-cell recordings require an optical fiber core diameter at the fiber end comparable with the size of the cell under observation. The electrode tip has to be of the similar size and in close proximity to the fiber core. One way to achieve those specifications is by making a dual core optical fiber having the light guiding core and the capillary within its claddinga b, and pulling or tapering one fiber end into the small diameter tip. When the capillary is filled with electrolyte, the fiber end becomes a usable single-cell opto-electric interface smaller than the cell itself.

More

Single-cell Opto-electric Recording