Optogenetically Synchronized Electrophysiology

The systems that combine optogenetics with electrophysiological recordings open-up new possibilities for neuroscience. They require delivery of appropriate optical signals to the point of interest within the neural tissue and detection and processing of the electrical spikes from neural activity. The system definition starts from the chronically...

The systems that combine optogenetics with electrophysiological recordings open-up new possibilities for neuroscience. They require delivery of appropriate optical signals to the point of interest within the neural tissue and detection and processing of the electrical spikes from neural activity. The system definition starts from the chronically implanted opto-electric cannula for behaving animals or from the opto-electric probes for in-vitro or fixed animal. For behaving animals, there is the tethered and the wireless/fiberless option.

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Optogenetically Synchronized Electrophysiology 

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  • Fiberless & Wireless

    Tethering lab animals with fibers and wires compromises their “freely moving” status for behaviour studies. Going wireless and fiberless effectively removes those limitations. Fi-Wi OSE system features the opto-electric cannula with one­ LED and up to four recording electrodes, the fiberless and wireless headstage for communication between the cannula and the base station, and finally the base station that configures the stimulation and recording parameters and displays the real-time data. Typically one needs at least two headstages so that one can be charged while the other is in use. The opto-electric cannulas are custom made for specific experiments and they might not be re-usable after chronic implantation